Distribution of diandric and digynic triploidy depending on gestational age
نویسندگان
چکیده
منابع مشابه
Triploidy—Observations in 154 Diandric Cases
Hydatidiform moles (HMs) are abnormal human pregnancies with vesicular chorionic villi, imposing two clinical challenges; miscarriage and a risk of gestational trophoblastic neoplasia (GTN). The parental type of most HMs are either diandric diploid (PP) or diandric triploid (PPM). We consecutively collected 154 triploid or near-triploid samples from conceptuses with vesicular chorionic villi. W...
متن کاملPrenatal detection of fetal triploidy from cell-free DNA testing in maternal blood.
OBJECTIVE To investigate potential performance of cell-free DNA (cfDNA) testing in maternal blood in detecting fetal triploidy. METHODS Plasma and buffy coat samples obtained at 11-13 weeks' gestation from singleton pregnancies with diandric triploidy (n=4), digynic triploidy (n=4), euploid fetuses (n=48) were sent to Natera, Inc. (San Carlos, Calif., USA) for cfDNA testing. Multiplex polymer...
متن کاملDigynic triploidy: utility and challenges of noninvasive prenatal testing
Low fraction fetal DNA in noninvasive prenatal testing in the context of fetal growth restriction and multiple congenital anomalies should alert medical professionals to the possibility of digynic triploidy. Single-nucleotide polymorphism microarray can detect the parental origin of triploidy and explain its mechanism.
متن کاملInfluence of diandric and digynic triploid genotypes on early mouse embryogenesis.
Standard micromanipulatory techniques were used to produce tripronucleate diandric and digynic triploid mouse conceptuses. When these were transferred to suitable recipients, most implanted. A wide range of embryonic stages from the primitive streak to the 15- to 25-somite stage were isolated in both triploid series in otherwise identical recipients. In the diandric triploid series, all of the ...
متن کاملPrenatal Detection of Fetal Triploidy from Cell-Free DNA Testing in Maternal Blood
Objective: To investigate potential performance of cell-free DNA (cfDNA) testing in maternal blood in detecting fetal triploidy. Methods: Plasma and buffy coat samples obtained at 11–13 weeks’ gestation from singleton pregnancies with diandric triploidy (n = 4), digynic triploidy (n = 4), euploid fetuses (n = 48) were sent to Natera, Inc. (San Carlos, Calif., USA) for cfDNA testing. Multiplex p...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2021
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-021-02202-4